Dr. Christopher Stanley
Clifford Shull Fellow
Education
PhD in Polymer Science and Engineering, the University of Massachusetts, in Amherst
Description of Research
Dr. Stanley uses neutron and x-ray scattering techniques to study the influence of osmolytes and their osmotic stress on the structure, dynamics, and thermodynamics of biological systems. His current studies include the self-assembly of aggregating, amyloid-like proteins and peptides. Other research includes the hydration and energetics associated with protein conformation and hydration forces between biopolymer liquid crystals.
Selected Publications
C. Stanley and D. C. Rau, Assessing the interaction of urea and protein-stabilizing osmolytes with the nonpolar surface of hydroxypropylcellulose, Biochemistry 47 6711–6718 (2008)
C. Stanley, S. Krueger, V. A. Parsegian, and D. C. Rau, Protein structure and hydration probed by SANS and osmotic stress, Biophys. J. 94 2777–2789 (2008)
C. B. Stanley and H. H. Strey, Electrostatically driven self-assembly of hybrid DNA-elastin liquid crystals, Soft Matter 4 241–244 (2008)
C. B. Stanley and H. H. Strey, Osmotically induced helix-coil transition in poly(glutamic acid), Biophys. J. 94 4427–4434 (2008)
B. A. Todd, N. Y. Sidorova, C. B. Stanley, and D. C. Rau, Hydration Forces in Biology, Chapter in Wiley Encyclopedia of Chemical Biology, John Wiley and Sons, Inc. (Dec. 2008)
C. Stanley and D. C. Rau, Preferential hydration of DNA: The magnitude and distance dependence of alcohol and polyol interactions, Biophys. J. 91 912–920 (2006)
C. B. Stanley, H. Hong, and H. H. Strey, DNA cholesteric pitch as a function of density and ionic strength, Biophys. J. 89 2552–2557 (2005)
C. B. Stanley and H. H. Strey, Measuring osmotic pressure of poly(ethylene glycol) solutions by sedimentation equilibrium ultracentrifugation, Macromolecules 36 6888–6893 (2003)
