Biological Small-Angle Neutron Scattering Instrument (Bio-SANS)
(CG-3)

		CG-3 Fact sheet (pdf)
Wavelength:		6 < < 30 Å
Wavelength resolution:		Δ/ = 8-45%
Q range:		0.002-1 Å-1
Sample-to-detector distance:		1-15 m
Detector:		2-D 3He
Detector size:		1 x 1 m
Detector resolution:		5.1 x 5.1 mm2 pixels
Max count rate:		200 kHz

Bio-SANS was designed and optimized for analysis of the structure, function, and dynamics of complex biological systems. Bio-SANS is the cornerstone of the Center for Structural Molecular Biology (CSMB) at Oak Ridge National Laboratory. The Bio-SANS instrument is supported by additional CSMB capabilities that include development of advanced computational tools for neutron analysis and modeling, as well as biophysical characterization and X-ray scattering infrastructure. A dedicated biological sample preparation laboratory is located adjacent to the instrument.

Detector tanks for the new SANS instruments at HFIR. The Bio-SANS detector is on the right.

Applications

• Bio-macromolecules and their assemblies
  -Protein complexes
  -Protein/DNA complexes
  -Lipids
  -Viruses
  -Carbohydrates
    
• Hierarchical biological structures
  -Gels
  -Fibers and fibrils
  -Vesicles
  -Microemulsions
   
• Membrane diffraction
   
• Biomimetic and bio-inspired systems

Contacts

Volker Urban, Instrument Scientist

Gary Lynn, Instrument Scientist

William Heller, Instrument Scientist

Dean Myles, Center Director