The Biological Small-Angle Neutron Scattering Instrument at HFIR
Bio-SANS was designed and optimized for analysis of the structure, function, and dynamics of complex biological systems. Bio-SANS is the cornerstone of the Center for Structural Molecular Biology (CSMB) at Oak Ridge National Laboratory. The Bio-SANS instrument is supported by additional CSMB capabilities that include development of advanced computational tools for neutron analysis and modeling, as well as biophysical characterization and X-ray scattering infrastructure. A dedicated biological sample preparation laboratory is located adjacent to the instrument.
Bio-macromolecules and their assemblies
- Protein complexes
- Protein/DNA complexes
Hierarchical biological structures
- Fibers and fibrils