Shuo Qian

Shuo Qian

Beam line: CG-3 BIO-SANS

Position: Instrument Scientist

Instrument: Biological Small-Angle Neutron Scattering Instrument

Group: Energy and the Environment

Facility: High Flux Isotope Reactor

Contact: or (865) 241-1934

​2013-Present The Bio-SANS Instrument Scientist and Staff Scientist, Center for Structural Molecular Biology, Oak Ridge National Laboratory

2012-2013 Career-development Instrument Scientist for the Bio-SANS, Center for Structural Molecular Biology, Oak Ridge National Laboratory

2009-2011 Postdoctoral Research Fellow, Chemical Sciences Division and Neutron Scattering Sciences Division, Oak Ridge National Laboratory


2009 ​​Ph.D. in Physics, Rice University Houston, TX

2004 B.S in Applied Physics, University of Science and Technology of China Hefei, Anhui, China


​Biophysics, membrane structure, membrane-active peptide and protein, protein structure

X-ray/neutron scattering/diffraction techniques and instrumentations, computer simulation and modeling

Selected Publications

S. Qian, D. K. Rai, W. T. Heller,"Alamethicin Disrupts the Cholesterol Distribution in Dimyristoyl Phosphatidylcholine Cholesterol Lipid Bilayers", J. Phy. Chem. B (2014) 118 (38), pp 1120011208

Heller, W. T., Urban, V. S., Lynn, G. W., Myles, D. A., Pingali, S. V., Qian, S., Littrell, K. C., Melnichenko, Y. B., Wignall, G. D., Buchanan, M. V., Selby, D. L. and Butler, P. D.,"The Bio-SANS Small-Angle Neutron Scattering Instrument at the High Flux Isotope Reactor at Oak Ridge National Laboratory", J. Appl. Crystallogr. (2014) 47 (4)

F. Giusti, J. Rieger, L. J. Catoire, S. Qian, A. N. Calabrese, T. G. Watkinson, M. Casiraghi, S. E. Radford, A. E. Ashcroft, J.-L. Popot "Synthesis, Characterization and Applications of a Perdeuterated Amphipol",J.Membrane Biol. (2014) 247 (4)

S. Qian, H.W. Huang,"A Novel Phase of Compressed Bilayers That Models the Pre-Stalk Transition State of Membrane Fusion", Biophys. J. (2012) 102, 48-55

S. Qian, W. Wang, L. Yang, H.W. Huang,"Structure of transmembrane pore induced by Bax derived peptide: Evidence for lipidic pores", Proc. Nat. Acad. Sci. U.S.A (2008) 105, 17379-17383

S. Qian, W. Wang, L. Yang, H.W. Huang,"Structure of the Alamethicin Pore Reconstructed by X-Ray Diffraction Analysis", Biophys. J. (2008) 94, 3512-3522

H. L. Li, K. Q. Ruan, Q. Wang, Y. Chen, S. Qian, Y. Yu, S. L. Huang, Z. Zheng, C. Y. Wang, L. Z. Cao,"Out-of-plane Transport in Bi2xPbxSr2Co2Oy Single Crystals",Physica Status Solidi (B) (2003) 240, 596

Awards, Honors and Memberships


Biophysical Society
American Crystallographic Association
American Physical Society
Neutron Scattering Society of America